1961
Grassmann, W., Hannig, K. and Engel, J.:
Das quantitative Verhältnis zwischen α- und β-Komponente des denaturierten, löslichen Kollagens in der Ultrazentrifuge sowie Beschreibung einer schnellen sedimentierenden ϒ-Komponente Z. physiol. Chem. 324, 284-288 (1961)
Engel, J.:
Untersuchungen des Mechanismus der Denaturierung und Renaturierung von löslichem Kollagen mit der Lichtstreumethode Z. physiol. Chem. 325, 287-288 (1961)
Hannig, K. and Engel, J.:
Physikalisch-chemische Untersuchungen an Tropokollagenlösungen Das Leder 12, 213-222 (1961)
1962
Engel, J.:
Physikalisch-chemische Untersuchungen an Tropokollagenlösungen
Dissertation Universität München (1962)
Engel, J.:
Investigation of the denaturation and renaturation of soluble collagen by light scattering Arch. Biochem. Biophys. 97, 150-158 (1962)
Engel, J.:
Ueber den Einfluss des Denaturierungsgrades und der Renaturierungsbedingungen auf die Rückbildung kollagener Strukturen
Z. physiol. Chemie 328, 94-96 (1962)
Engel, J., Grassmann, W., Hannig, K. and Kühn, K.:
Zur Bildung von Fibrillen und Long Spacing-Segmenten aus renaturierten Tropokollagenlösungen Z. physiol. Chem. 329, 69-75 (1962)
1963
Engel, J. and Beier, G.:
Vergleich der molekularen Daten von Tropokollagen verschiedener Kalbshäute im nativen und denaturierten Zustand Z. physiol. Chem. 334, 201-214 (1963)
1964
Engel, J. and Beier, G.:
Die Rückbildung der Sekundär- und Tertiärstruktur denaturierter Eiweissmoleküle Kolloid-Zeitschrift 197, 7-14 (1964)
Kühn, K., Engel, J., Zimmermann, B. und Grassmann, W.:
Renaturation of soluble collagen. III. Reorganization of native collagen molecules from completely separated units Arch. Biochem. Biophys. 105, 387-403 (1964)
Beier, G., Engel, J. and Grassmann, W.:
Zum Mechanismus der Bildung der Tripelhelix des Kollagens aus den denaturierten Komponenten Meeting Proceedings, p. 101, Deut. Ges. Biophys., Oesterr. Ges. Reine u. Angew. Biophys., Schweiz. Ges. Strahlenbiol., Wien Sept. 1964, Collag. Cur. 5, 310 (1964)
1965
Grassmann, W., Kühn, K., Engel, J. and Zimmermann, B.:
Denaturierung und Renaturierung des Kollagens Das Leder 16, 32-38 (1965)
Engel, J., Kurtz, J., Traub, W., Berger, A. and Katchalski, E.:
On the mechanism of collagen denaturation and renaturation and on conformational changes in related polypeptides.
In "Structure and function of connective and skeletal tissue" (ed. S. Fitton Jackson), Proceeding of an Advanced Study Institute Organized under the Auspice of NATO, St. Andrews, June 1964. Butterworth, London, pp. 241-329 (1965)
Grassmann, W., Engel, J., Hannig, K., Hörmann, H., Kühn, K. and Nordwig, A.:
Kollagen: a) in "Fortschritte der Chemie organischer Naturstoffe" (ed. L. Zechmeister), pp. 196-314, Springer Verlag, Wien, New York (1965) b) in "Progress in the Chemistry of Organic Natural Products" p. 245 (1965)
1966
Engel, J., Kurtz, K., Berger, A. and Katchalski, E.:
Polymers of tripeptides as collagen models, part II. Conformational changes of poly-(L-prolyl-glycyl-L-prolyl) in solution.
J. Mol Biol. 17, 255-272 (1966)
Beier, G. and Engel, J.:
The renaturation of soluble collagen. Products formed at different temperatures Biochemistry 5, 2744-2755 (1966)
Engel, J.:
Equilibrium and kinetic studies of the cooperative I = II transition in poly-L-proline
Biopolymers 4, 945-948 (1966
1967
Engel, J.:
Strukturumwandlungen in Systemen, welche die Polyprolin-II-Helix als Grundstruktur enthalten Habilitationsschrift, Universität München, 1967
Brunori, J., Engel, J. and Schuster, T.:
The effect of ligand binding on the optical rotatory dispersion of myoglobin, hemoglobin and isolated hemoglobin subunits J. Biol. Chem. 242, 773 (1967)
Prockop, D.J., Juva, K. and Engel, J.:
Enzymatic synthesis of hydroxyproline by the hydroxylation of poly-(L-prolyl-glycyl-L-prolyl) Z. physiol. Chem. 348, 553-560 (1967)
Kivirikko, K.I., Ganser, V., Engel, J. and Prockop, D.J.:
Comparison of poly-L-proline I and II as inhibitors of procollagen hydroxylase Z. physiol. Chem. 348, 1341-1344 (1967)
Engel, J.:
Conformational transitions of poly-L-proline and poly-(L-prolyl-glycyl-L-proline).
In "Conformation of Biopolymers" (ed. G.N. Ramachandran) Acad. Press, London, New York vol. 2, 483 (1967)
1968
Formanek, H. and Engel, J.:
Optical rotatory dispersion of a respiratory hemeprotein of chironomus thummi Biochim. Biophys. Acta 160, 151-158 (1968)
Engel, J.:
Das Polytripeptid Poly-(L-prolyl-glycyl-L-prolin) als Modell des Kollagens
Das Leder 19, 21-28 (1968)
1969
Engel, J.:
Hydrogen bonds in biological systems.
In "Proceedings of the International Symposium on Physics of Ice". Munich, Sept. 1968, pp. 138-151, Plenum Press, New York, 1969
Hänisch, G., Engel, J., Brunori, M. and Fasold, H.:
Ligand induced conformational changes in various normal and modified hemoglobins as indicated by changes in optical rotatory dispersions Eur. J. Biochem. 9, 335-342 (1969)
Engel, J.:
Equilibrium and kinetics of cooperative transitions in polypeptides and proteins
10th European Peptide Symposium, Padua, Sept. 1969, pp. 231-254, Acad. Press (N. Holland Publ. Co.) (1969)
Strassmair, H., Knof, S. and Engel, J.: Different binding of solvent to the peptide carbonyl group in different conformational environments induces the helix I = helix II Transition of poly-L-proline Z. physiol. Chem. 350, 1153-1154 (1969)
Strassmair, H., Engel, J. and Zundel, G.:
Binding of various alcohols to the peptide CO-group of poly-L-proline in the I and II conformation Biopolymers 8, 237 (1969)
1970
Ganser, V., Engel, J., Winkelmair, D. and Krause, G.:
Cooperative transition between two helical conformations in a linear system: Poly-L-proline I = II. Equilibrium studies. Biopolymers 9, 329-353 (1970)
Engel, J.:
Helix formation in collagen-like synthetic polypeptides.
In "The Chemistry and Molecular Biology of the Intercellular Matrix" (ed. E.A. Balazs) Acad. Press, London, New York, 1, 127 (1970)
Engel, J. and Schwarz, G.:
Kooperative Konformationsumwandlungen von linearen Biopolymeren. a) Angew. Chem. 82, 468-479 (1970) b) Internat. Ed. 9, 389-400 (1970)
1971
Winkelmair, D., Engel, J. and Ganser, V.:
A cooperative transition between two helical conformations in a linear system: Poly-L-proline I = II. Kinetic studies Biopolymers 10, 721-737 (1971)
Strassmair, H., Engel, J. and Knof, S.:
Binding of alcohols to the peptide CO-group of poly-L-proline in the I and II conformation. Binding constants from infrared measurements in solution
Biopolymers 10, 1759-1776 (1971)
Engel, J., Liehl, E. and Sorg, C.:
Circular dichroism, optical rotatory dispersion and helix = coil transition of polytyrosine and tyrosine peptides in non-aqueous solvents
Eur. J. Biochem. 21, 22-30 (1971)
Engel, J.:
Aenderung der Raumstruktur bei Proteinen
Umschau in Wissenschaft + Technik 14, 533 (1971)
1972
Knof, S., Strassmair, H., Engel, J., Rothe, M. and Steffen, K.D.:
Binding of benzyl alcohol to the peptide CO-group of cyclotri-L-prolyl studied by infrared spectroscopy
Biopolymers 11, 731-733 (1972)
Bode, W., Engel, J. and Winkelmair, D.:
A model of bacterial flagella based on small angle x-ray scattering and hydrodynamic data which indicate an elongated shape of the flagellin protomer Eur. J. Biochem. 26, 313-327 (1972)
Schwarz, G. and Engel, J.:
Kinetik kooperativer Konformationsumwandlungen von linearen Biopolymeren a) Angew. Chem. 84, 615-623 (1972) b) Internat. Ed. 11, 568-575 (1972)
Engel, J. and Winkelmair, D.:
Cooperative association.
In "Protein-Protein Interactions" (eds. R. Jaenicke, U.E. Helmreich). Colloquium Ges. Biol. Chem. Mosbach April 1972, pp. 159-181, Springer Verlag, Heidelberg (1972)
Engel, J. and Winkelmair, D.:
Equilibrium and kinetics of cooperative binding and cooperative association. In "Enzymes: Structure and Function" (eds. J. Dreutz, R.A. Oosterbaan and C. Veeger). Proceedings of the 8th FEBS Meeting, pp. 239-254), North Holland, Amsterdam (1972)
1974
Engel, J., Quast, U., Heumann, H., Krause, G. and Steffen, E.:
Kinetic studies of the binding of bovine basic pancreatic trypsin inhibitor to α-chymotrypsin. In "Proceedings of the 2nd Internat. Research Conference on Proteinase Inhibitors" (eds. H. Fritz, H. Tschesche, L.J. Greene and E. Truscheit). Oct. 1973, pp. 412-419, Springer Verlag, Heidelberg (1974)
Quast, U., Engel, J., Heumann, H., Krause, G. and Steffen, E.:
Kinetics of the interaction of bovine pancreatic trypsin inhibitor (Kunitz) with α-chymotrypsin Biochemistry 13, 2512-2520 (1974)
Knof, S. and Engel, J.:
Conformational stability, partial specific volumes and spectroscopic properties of poly-L-proline, poly-L-hydroxyproline and some of its O-acyl-derivatives in various solvent systems Israel J. of Chem. 12, 165-177 (1974)
Weidner, H., Engel, J. and Fietzek, P.:
Mechanism of the triple helix = coil transition of short peptides with collagen-like sequence.
In "Peptides, Polypeptides & Proteins" (eds. E.R. Blout, F.A. Bovey, M. Godman, N. Lotan). Proceedings of the Rehovot Symposium on Polyamino-Acids, pp. 419-435, May (1974)
1975
Quast, U., Engel, J., Steffen, E., Mair, G. and Tschesche, H.:
Kinetics of the binding of basic pancreatic trypsin inhibitor (Kunitz) in which the reactive peptide bonds Lys 15-Ala 16 is cleaved to α-Chymotrypsin and ß-Trypsin
Eur. J. Biochem. 52, 505-510 (1975)
Quast, U., Engel, J., Steffen, E., Mair, G. and Tschesche, H.:
The effect of cleaving the reactive peptide bond Lys 15-Ala 16 on the conformation of pancreatic trypsin inhibitor (Kunitz) as revealed by solvent perturbation spectra, circular dichroism and fluorescence
Eur. J. Biochem. 52, 511-514 (1975)
Wegner, A. and Engel, J.:
Kinetics of the cooperative association actin to actin filaments
Biophys. Chem. 3, 215-225 (1975)
Waechter, F. and Engel, J.:
The kinetics of the exchange of G-actin bound 1, N6-ethenoadenosine 5'-triphosphate with ATP as followed by fluorescence
Eur. J. Biochem. 57, 453-459 (1975)
Bruckner, P., Rutschmann, B., Engel, J. and Rothe, M.:
A classical synthesis of the collagen-like peptides with the sequence Z (GlyProPro)nOBut and their characterization with circular dichroism and ultracentrifugation
Helv. Chim. Acta 58, 1276 (1975)
1976
Quast, U., Engel, J., Mair, G. and Tschesche, H.:
Kinetics of the interaction of virgin and modified bovine trypsin kallikrein inhibitor (Kunitz) with ß-trypsin
Protides of the Biological Fluids, 23rd Colloquium, Pergamon Press, p. 57 (1976)
Engel, J., Chen, H.-T., Prockop, D.J. and Klump, H.:
The triple helix = coil conversion of collagen-like poly-tripeptides in aqueous and nonaqueous solvents. Comparison of the thermodynamic parameters and the water binding of (L-Pro-L-Pro-Gly)n and (L-Pro-L-Hyp-Gly)n
Biopolymers 16, 601-622 (1977)
Maeda, H., Engel, J. and Schramm, H.J.:
Kinetics of dimerization of the variable fragment of the Bence-Jones protein Au
Eur. J. Biochem. 69, 133-139 (1976)
Bösterling, B., Engel, J., Steinemann, A. and Schramm, H.J.:
Extrinsic signals for monitoring the association reaction of proteins as introduced by fluorescent and non-fluorescent labels
Hoppe-Seyler's Z. physiol. Chem. 357, 1283-1296 (1976)
Bösterling, B. and Engel, J.:
Influence of various fluorescent and non-fluorescent labels on the kinetics of the complex formation of α -chymotrypsin with basic pancreatic trypsin inhibitor (Kunitz)
Hoppe-Seyler's Z. physiol. Chem. 357, 1297-1307 (1976)
Engel, J. and Wegner, A.:
Kinetics of the cooperative linear association of actin
Studia Biophysica 57, 179-185 (1976)
1977
Maeda, H., Schmidt-Kessen, A., Engel, J. and Jaton, J.-C.:
Kinetics of binding of oligosaccharides to a homogeneous pneumococcal antibody: Dependence on antigen chain length suggests a labile intermediate complex
Biochemistry 16, 4086-4089 (1977)
Waechter, F. and Engel, J.:
Association kinetics and binding of constants of nucleoside triphosphates with G-actin
Eur. J. of Biochemistry 74, 227 (1977)
Engel, J., Bruckner, P., Becker, U., Timpl, R. and Rutschmann, B.:
Physical properties of the amino terminal precursor-specific portion of type I procollagen
Biochemistry 16, 4026-4033 (1977)
Olsen, B., Guzman, N., Engel, J., Condit, Ch. and Aase, S.:
Purification and characterization of a peptide from the carboxyterminal region of chick tendon procollagen type I
Biochemistry 16, 3030 (1977)
Engel, J., Fasold, H., Hulla, E.W., Waechter, F. and Wegner, A.:
The polymerization reaction of muscle actin
Molec. and Cell. Biochemistry 18, 3-13 (1977)
1978
Quast, U., Engel, J., Steffen, E., Tschesche, H. and Kupfer, S.:
Stopped flow kinetics of the re-synthesis of the reactive site peptide bond in kallikrein inhibitor (Kunitz) by ß-trypsin
Biochemistry 17, 1675-1682 (1978)
Quast, U., Engel, J., Steffen, E., Tschesche, H. and Kupfer, S.:
Kinetics of the interaction of α-chymotrypsin with trypsin kallikrein inhibitor (Kunitz) in which the reactive site peptide bond Lys-5-Ala 16 is split
Eur. J. Biochem. 86, 353-360 (1978)
Bruckner, P., Bächinger, H.P., Timpl, R. and Engel, J.:
Three conformationally distinct domains in the amino-terminal segment of type III procollagen and its rapid triple helix = coil transition
Eur. J. Biochem. 90, 595-603 (1978)
Bächinger, H.P., Bruckner, P., Timpl, R. and Engel, J.:
The role of cis-trans isomerization of peptide bonds in the coil = triple helix conversion of collagen
Eur. J. Biochem. 90, 605-613 (1978)
Maeda, H., Steffen, E. and Engel, J.:
Kinetics of dimerization of the Bence-Jones Protein Au
Biophys. Chem. 9, 57-64 (1978)
Wright, J.K., Engel, J., Brandt, D.Ch. and Jaton, J.-C.:
Independence of the binding of domain-specific ligands to Fab and Fc suggest that antigen-induced effects in IgG antibodies are not allosteric
FEBS Lett. 90, 79-83 (1978)
Wright, J.K., Engel, J. and Jaton, J.-C.:
Selective reduction and proteolysis in the hinge region of liganded and unliganded antibodies. Identical kinetics suggest lack of major conformationel change in the hinge region
Eur. J. Immunol. 8, 309-314 (1978)
1979
Bösterling, B. and Engel, J.:
Kinetic studies of the helix-coil transition of fluorescent labeled poly(-L-lysine) by the temperature-jump technique
Biophys. Chem. 9, 201-209 (1979)
Wright, J.K., Engel, J. and Jaton, J.-C.:
Purification, characterization and reassembly of the bacteriophage T4D tail sheath protein P18
J. Mol. Biol. 128, 247-258 (1979)
Arisaka, F., Tschopp, J., van Driel, R. and Engel, J.:
Reassembly of the bacteriophage T4 tail from the core-baseplate and the monomeric sheath protein P18: A cooperative association process
J. Mol. Biol. 132, 369-386 (1979)
Stankowski, S. and Engel, J.:
Multisite proteins and randomly coiled polymeric ligands. Chain length dependence of binding constants
Biophys. Chem. 9, 383-391 (1979)
Neidl, C. and Engel, J.:
Exchange of ADP, ATP and 1:N6-ethenoadenosine 5'-triphosphate at G-actin. Equilibrium and kinetics
Eur. J. of Biochem. 101, 163-169 (1979)
1980
Wright, J.K., Tschopp, J., Jaton J.-C. and Engel, J.:
Dimeric, trimeric and tetrameric complexes of immunoglobulin G fix complement
Biochem. J. 187, 775-780 (1980)
Engel, J. and Schalch, W.:
Determination of antibody binding constants from Farr test and other radioimmunoassays. A theoretical and experimental analysis
J. Molec. Immunol. 17, 675-680 (1980)
Bächinger, H.P., Bruckner, P., Timpl, R., Prockop, D.J. and Engel, J.:
Folding mechanism of the triple helix in type III collagen and type III pN-collagen. Role of disulfide bridges and peptide bond isomerization
Eur. J. Biochem. 106, 619-632 (1980)
Tschopp, J., Villiger, W., Lustig, A., Jaton, J.-C. and Engel, J.:
Antigen-independent binding of immunoglobulin G-dimers to C1q as studied by sedimentation equilibrium, cvomplement fixation and electronmicroscopy
Eur. J. of Immunol. 10, 529-535 (1980)
Risteli, J., Bächinger, H.P., Engel, J., Furthmayr, H. and Timpl, R.:
7S collagen: Characterization of an unusual basement membrane structure
Eur. J. Biochem. 108, 239-250 (1980)
Tschopp, J., Schulthess, T., Engel, J. and Jaton, J.-C.:
Antigen-independent activation of the first component of complement C1 by chemically cross-linked rabbit IgG-oligomers
FEBS Lett. 112, 152-154 (1980)
Engel, J., Bächinger, H.P., Bruckner, P. and Timpl, R.:
The role of disulfide bridges and cis = trans isomerization of peptide bonds in collagen folding
In "Protein Folding" (ed. R. Jaenicke) Elsevier North-Holland Biomedical Press, pp. 345-368 (1980)
Tschopp, J. and Engel, J.:
Kinetics of the cooperative association of T4 tail sheath protein P18 to polysheaths
Biophys. Chem. 12, 307-315 (1980)
Tschopp, J., Villiger, W., Fuchs, H., Kilcherr, E. and Engel, J.:
Electronmicroscopic and ultracentrifugal studies on the assembly of the subcomponents C1r and C1s of the first component of complement (C1)
Proc. Natl. Acad. Sci. (USA) 77, 7014-7017 (1980)
1981
Arisaka, F., Engel, J. and Klump, H.:
Contraction and dissociation of the bacteriophage T4 tail sheath induced by heat and urea
Proceedings of the 7th Biannual Bacteriophage Assembly Meeting, Alan R. Liss Inc., New York, pp. 365-379 (1981)
Engel, J., Odermatt, E., Engel, A., Madri, J.A., Furthmayr, H., Rohde, H. and Timpl, R.:
Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix
J. Mol. Biol. 150, 97-120 (1981)
1982
Engel, J.:
Thermodynamics and kinetics of self assembly.
Thermodynamik und Kinetik von Self-Assembly Vorgängen
Neuauflage des Lehrbuchs "Biophysik" (eds. Hoppe et al.), Springer Verlag, pp. 421-425 (1982)
Engel, J.:
Conformational transitions in biopolymers.
Konformationsumwandlungen in Biopolymeren
Neuauflage des Lehrbuchs "Biophysik" (Springer Verlag) (eds. Hoppe et al.) pp. 242-252 (1982)
Odermatt, E., Furthmayr, H., Timpl, R., Rohde, H., Ott, U. and Engel, J.:
Shape, domain structure and flexibility of laminin.
10th Workshop Conference Hoechst, New Trends in Basement Membrane Research, May 11-14, 1981, Eibsee, FRG (eds. K, Kühn, H. Schöne and R. Timpl) Raven Press, New York, pp. 79-86 (1982)
Kilchherr, E., Fuchs, H., Tschopp, J. and Engel, J.:
Dissociation of C1 and concentration dependence of its activation kinetics
J. Molec. Immunol. 19, 683-691 (1982)
Odermatt, E., Engel, J., Richter, H. and Hörmann, H.:
Shape, conformation and stability of fibronectin fragments determined by electron microscopy, circular dichroism and ultracentrifugation
J. Mol Biol. 159, 109-123 (1982)
Ott, U., Odermatt, E., Engel, J., Furthmayr, H. and Timpl, R.:
Protease resistance and conformation of laminin
Eur. J. Biochem. 123, 63-72 (1982)
1983
Furthmayr, H., Wiedemann, H., Timpl, R., Odermatt, E. and Engel, J.:
Electron microscopical approach to a structural model of intima (type VI) collagen
Biochem. J. 211, 303-311 (1983)
Weiss, V. and Engel, J.:
Heparin stimulated modification of C1-inhibitor by subcomponent C1s of human complement
Hoppe Seyler's Z. Physiol. Chem. 364, 295-301 (1983)
Markovic, Z., Engel, J., Richter, H. and Hörmann, H.:
Discrimination of different domains in fibronectin on the basis of their stability against urea denaturation
Hoppe Seyler's Z. Physiol. Chem. 364, 551-561 (1983)
Timpl, R., Engel, J. and Martin, G.R.:
Laminin - a multifunctional protein of basement membranes
TIBS 8, 207-209 (1983)
1984
Hofmann, H., Voss, T., Kühn, K. and Engel, J.:
Localization of flexible sites in threadlike molecules from electron micrographs: Comparison of interstitital, basement membrane and intima collagens
J. Mol. Biol. 172, 325-343 (1984)
Markovic, Z., Lustig, A., Engel, J., Richter, H. and Hörmann, H.:
Shape and stability of fibronectin in solutions of different pH and ionic strength
Hoppe-Seyler's Z. Physiol. Chem. 364, 1795-1804 (1983)
Weber, S., Engel, J., Wiedemann, H., Glanville, R.W. and Timpl, R.:
Subunit structure and assembly of the globular domain of basement membrane collagen type IV. Eur. J. Biochem. 139, 401-410 (1984)
Timpl, R., Fujiwara, S., Dziadek, M., Aumailley, M., Weber, S. and Engel, J.:
Laminin, proteoglycan and collagen IV: Structural models and their interactions
Ciba Foundation Symp. 108: Basement Membranes and Cell Movement, Pitman, London, pp. 25-37 (1984)
Fujiwara, S., Wiedemann, H., Timpl, R., Lustig, A. and Engel, J.:
Structure and interactions of heparan sulfate proteoglycans from a mouse tumor basement membrane
Eur. J. Biochem. 143, 145-157 (1984)
Wiedemann, H., Paulsson, M., Timpl, R., Engel, J. and Heinegard, D.:
Domain structure of cartilage proteoglycans visualized by rotary shadowing of intact and fragmented molecules
Biochem. J. 224, 331-333 (1984)
1985
Paulsson, M., Deutzmann, R., Timpl, R., Dalzoppo, D., Odermatt, E. and Engel, J.:
Evidence for coiled-coil α -helical regions in the long arm of laminin
EMBO J. 4, 309-316 (1985)
Ingham, K.C., Landwehr, R. and Engel, J.:
Interaction of fibronectin with C1q and collagen: Effects of ionic strength and denaturation of the collagenous component
Eur. J. Biochem. 148, 219-224 (1985)
Timpl, R., Oberbäumer, I., Von der Mark, H., Bode, W., Wick, G., Weber, S. and Engel, J.:
Structure and biology of the globular domain of basement membrane collagen type IV
Ann. New York Acad. Sci. 460, 58-72 (1985)
Engel, J., Furthmayr, H., Odermatt, E., Von der Mark, H., Aumailley, M., Fleischmajer, R. and Timpl, R.:
Structure and macromolecular organization of type VI collagen
Ann. New York Acad. Sci. 460, 25-37 (1985)
Engel, J.:
Domain Organizations of laminin and fibronectin. Two multifunctional proteins of the extracellular matrix
In: Multidomain Proteins (eds. L. Patthy, P. Friedrich). Proc. of the UNESCO Workshop on Structure and Function of Proteins, Akademiai Kiado, Budapest, pp. 89-102 (1986)
Murray, L.W., Engel, J. and Tanzer, M.L.:
Annelid cuticle collagen: A very long protein
Ann. New York Acad. Sci. 460, 478 (1985)
Kilchherr, E., Hofmann, H., Steigemann, W. and Engel, J.:
A structural model of the collagen-like region of C1q comprising the kink region and the fibre-like packing of the six triple helices
J. Mol. Biol. 186, 403-415 (1985)
Dziadek, M., Paulsson, M., Deutzmann, R., Timpl, R., Weber, S. and Engel, J.:
Structure and function of nidogen
In "Basement Membranes (ed. S. Shibata) Elsevier Science Publishers, Amsterdam, pp. 13-23 (1985)
Markovic-Housley, Z., Schulthess, T., Engel, J., Richter, H. and Hörmann, H.:
Different susceptibility of inter and intra chain disulfide bonds in native fibronectin and effect of their reductive cleavage on conformation
Biol. Chem. Hoppe Seyler 366, 985-991 (1985)
1986
Weiss, V., Fauser, C. and Engel, J.:
Functional model of subcomponent C1 of human complement
J. Mol. Biol. 189, 573-581 (1986)
Paulsson, M., Deutzmann, R., Dziadek, M., Nowack, H., Timpl, R., Weber, S. and Engel, J.:
Purification and structural characterization of intact and fragmented nidogen obtained from a tumor basement membrane
Eur. J. Biochem. 156, 467-478 (1986)
Paulsson, M., Fujiwara, S., Dziadek, M., Timpl, R., Peijler, G., Backström, G., Lindahl, U. and Engel, J.:
Structure and function of basement membrane proteoglycans
Ciba Foundation Symp. "Functions of the Proteoglycans" January 14-16 (eds. E. David and J. Whelan) John Wiley, London, pp. 189-203 (1986)
Quinlan, R.A., Hatzfeld, M., Franke, W.W., Lustig, A., Schulthess, T. and Engel, J.:
Characterisation of dimer subunits of intermediate filament proteins
J. Mol. Biol. 192, 337-340 (1986)
1987
Engel, J. and Furthmayr, H.:
Electron microscopy and other physical methods for the characterization of extracellular matrix components: Laminin, fibronectin, collagen IV, collagen VI and proteoglycans
Meth. Enzymol. 145, 3-78 (1987)
Engel, J.:
Folding and unfolding of collagen triple helices
In "Advances in Meat Research" Van Nostrand Reinhold Company, New York, vol. 4, pp. 145-158 (1987)
Gerber-Huber, S., Nardelli, D., Haefliger, J.-A., Cooper, D.N., Givel, F., Germond, J.-E., Engel, J. and Wahli, W.:
Precursor-product relationship between vitellogenin and yolk proteins derived from the complete sequence of a xenopus vitellogenin gene
Nucleic Acids Red. 15, 4737-4760 (1987)
Paulsson, M. Mörgelin, M., Wiedemann, H., Beardmore-Gray, M., Dunham, D., Hardingham, T.E., Heinegard, D., Timpl, R. and Engel, J.:
Extended and globular protein domains in cartilage proteoglycans
Biochem. J. 245, 763-772 (1987)
Paulsson, M., Aumailley, M., Deutzmann, R., Timpl, R., Beck, K. and Engel, J.:
Laminin-nidogen complex: Extraction with chelating agents and structural characterization
Eur. J. Biochem. 166, 11-19 (1987)
Timpl, R. and Engel, J.:
Collagen type VI
In "Structure and Function of Collagen Types" (eds. R. Mayne and R.E. Burgeson) Biol. Extracell. Matrix, Academic Press, New York, pp. 105-141 (1987)
Paulsson, M. Yurchenco, P., Ruben, G.C., Engel, J. and Timpl, R.:
Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane
J. Mol. Biol. 197, 297-313 (1987)
Weiss, V. and Engel, J.:
Functional models of the C1 complex. Consensus and disagreement
J. Mol. Biol. 195, 437-438 (1987)
Engel, J., Taylor, W., Paulsson, M., Sage, H. and Hogan, B.:
Calcium binding domains and calcium induced conformational transition of SPARC (osteonectin, BM-40), an extracellular glycoprotein expressed in mineralized and non mineralized tissues
Biochemistry 26, 6958-6965 (1987)
End, P., Panayotou, G., Timpl, R. and Engel, J.:
Growth factor like domains in laminin
Experientia 43, 636 (1987)
Hogan, B.L.M., Holland, P.W.H. and Engel, J.:
Structure and expression of SPARC (osteonectin, BM-40): a secreted Ca++-binding glycoprotein associated with extracellular matrix production
in: The Cell in Contact II: "Structure and Function of Adhesion Molecules". The Neurosciences Institute
Ringwald, M., Schuh, R., Vestweber, D., Eistetter, H., Lottspeich, F., Engel, J., Dölz, R., Jähnig, F., Epplen, J., Mayer, S., Müller, C. and Kemler, R.:
The structure of cell adhesion molecule uvomorulin: Insights into the molecular mechanism of Ca2+-dependent cell adhesion
EMBO J. 6, 3647-3653 (1987)
1988
Voss, T., Eistetter, H., Schäfer, K.P. and Engel, J.:
The macromolecular organization of natural and recombinant lung surfactant protein SP 28-36: structural homology with the complement factor Clq
J. Mol. Biol. 201, 219-227 (1988)
Mörgelin, M., Paulsson, M., Hardingham, T.E., Heinegard, D. and Engel, J.:
Cartilage Proteoglycans: Assembly with hyaluronate and link protein as studied by electron microscopy
Biochemical J. 253, 175-185 (1988)
Weber, S., Dölz, R., Timpl, R., Fessler, J.H. and Engel, J.:
Reductive cleavage and reformation of the inter- and intra-chain disulfide bonds in the globular hexameric domain NCl involved in network assembly of basement membrane collagen (type IV)
Eur. J. Biochem. 175, 229-236 (1988)
Schittny, J.C., Timpl, R. and Engel, J.:
High Resolution Immunoelectron Microscopic Localization of Functional Domains of Laminin, of Nidogen and Heparan Sulfate Proteoglycan in Epithelial Basement Membrane of Mouse Cornea Reveals Different Topological Orientations
J. Cell Biol., 107, 1599-1610 (1988)
Bruch, M., Weiss, V. and Engel, J.:
Plasma serine proteinase inhibitors (serpins) exhibit major conformational changes and a large increase in conformational stability upon cleavage at their reactive sites
J. Biol. Chem. 263, 16626-16630 (1988)
Dölz, R., Engel, J. and Kühn, K.:
Folding of Collagen IV
Eur. J. Biochem., 178, 357-366 (1988)
Vogel, B.E., Dölz, R., K.E. Kadler, Hojima, Y., Engel, J. and Prockop, D.J.
A Substitution of Cysteine for Glycine 748 of the α1 Chain Produces a Kink at This Site in the Procollagen I Molecule and an Altered N-Proteinase Cleavage Site over 225 nm Away
J. Biol. Chem. 263, 19249-19255 (1988)
1989
Panayotou, G., End, P., Aumailley, M., Timpl, R. and Engel, J.:
Domains of Laminin with Growth-Factor Activity
Cell 56, 93-101 (1989)
Odermatt, E. and Engel, J.:
Physical properties of fibronectin
In "Fibronectin" (ed. D.F. Mosher) Academic Press Inc. pp. 25-45 (1989)
Voss, T., Eistetter, H., Schäfer, K.P. and Engel, J.:
The Macromolecular Organization of Canine Lung Surfactant Protein SP 28-36; Structural Homology with the Complement Factor C1q
In: Proceedings of the International Symposium on Surfactant Replacement Therapy (B. Lachmann, ed.) Springer Verlag,
pp 345-350 (1988)
Engel, J.:
EGF-like domains in extracellular matrix proteins: Localized signals for growth and differentiation ?
FEBS Lett. 251, 1-7 (1989)
Bruch, M., Landwehr, R. and Engel, J.:
A fragment of laminin comprising the entire long arm.
In: Cytoskeletal and Extracellular Proteins (U. Aebi and J. Engel, eds.) pp. 108-109, Springer Verlag, Heidelberg (1989)
Hunter, I., Beck, K., Schulthess, T. and Engel, J.:
Triple coiled-coil regions of laminin: Specificity and chain stability.
In: Cytoskeletal and Extracellular Proteins (U. Aebi and J. Engel, eds.) pp. 106-107, Springer Verlag, Heidelberg (1989)
Bruch, M., Landwehr, R. and Engel, J.:
Dissection of laminin by cathepsin G into its long arm and short arm structures and localization of regions involved in calcium dependent stabilization and self-association
Eur. J. Biochem. 185, 271-279 (1989)
Ertl, H., Mengele, R., Wenzl, S., Engel, J. and Sumper, M.:
The extracellular matrix of volvox carteri: Molecular structure of the cellular compartment
J. Cell Biol. 109, 3493-3501 (1989)
1990
Dölz, R. and Engel, J.:
Nucleation, propagation and direction of triple helix formation collagens I, III and IV and in gelatin as monitored by electron microscopy.
Ann. N.Y. Acad. Sci. 580, 421-424 (1990)
Hunter, I., Schulthess, T., Bruch, M., Beck, K. and Engel, J.:
Evidence for a specific mechanism of laminin assembly
Eur. J. Biochem. 188, 205-211 (1990)
Mörgelin, M., Paulsson, M. and Engel, J.:
Assembly of cartilage proteoglycan with hyaluronate and structure of the central filament in proteoglycan aggregate
Biochem. Soc. Transact. 18, 204-207 (1990)
Beck, K., Hunter, I. and Engel, J.:
Structure and function of laminin: Anatomy of a multidomain glycoprotein
FASEB J. 4 148-160 (1990)
Kalb, E., Engel, J. and Tamm, L.K.
Binding of proteins to specific target sites in membranes measured by total internal reflection fluorescence microscopy
Biochemistry 29, 1607-1613 (1990)
Ozawa, M., Engel, J. and Kemler, R.:
Single amino acid substitutions in one Ca++-binding site of uvomorulin abolish the adhesive function Cell 63, 1033-1038 (1990)
1991
End, P. and Engel, J.:
Multidomain proteins of the extracellular matrix and cellular growth
In: "Receptors for Extracellular Matrix Proteins" (R.P. Mecham and J. McDonald, eds.) pp. 79-129, Academic Press (1991)
Engel, J. and Prockop, D.J.:
The zipper-like folding of collagen triple helices and the effects of mutations that disrupt the zipper Ann. Rev. Biophys. and Biophys. Chem. 20, 137-152 (1991)
Haas, C., Voss, T. and Engel, J.:
In vitro assembly and disulfide rearrangment of recombinant surfactant SP-A in vitro
Eur. J. Biochem. 197, 799-803 (1991)
Engel, J.:
Domains in proteins and proteoglycans of the extracellular matrix with functions in assembly and cellular activities Int. J. Biol. Macromol. 13, 147-151 (1991)
Mayer, U., Aumailley, M., Mann, K., Timpl, R. and Engel, J.:
Calcium-dependent binding of BM-40 (osteonectin, SPARC) to basement membrane collagen type IV Eur. J. Biochem. 198, 141-150 (1991)
Kalb, E. and Engel, J.:
Binding and calcium induced aggregation of laminin onto lipid bilayers J. Biol. Chem. 266, 19047-19052 (1991)
Gaill, F., Wiedemann, H., Mann, K., Kühn, K., Timpl, R. and Engel, J.:
Molecular characterization of cuticle and interstitial collagens from worms collected at deep sea hydrothermal vents J. Mol. Biol. 221, 209-223 (1991)
Kurz, E.M., Holstein, T.W., Petri, B.M., Engel, J. and David, C.N.:
Mini-collagens in hydra nematocytes J. Cell Biol. 115, 1159-1169 (1991)
Engel, J., Hunter, I., Schulthess, T., Beck, K., Dixon, T.W. and Parry, D.A.D.:
Assembly of laminin isoforms by triple and double stranded coiled-coil structures
Biochem. Soc. Transactions 19, 839-844 (1991)
Fox, J.W., Mayer, U., Nischt, R., Aumailley, M., Reinhardt, D., Wiedemann, H., Mann, K., Timpl, R., Krieg, T., Engel, J. and Chu, M.L.:
Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV
EMBO J. 10, 3137-3146 (1991)
Engel, J.:
Common structural motifs in proteins of the extracellular matrix
Current Opinion in Cell Biology 3, 779-785 (1991)
1992
Beck, K., Spring, J., Chiquet-Ehrismann, R., Engel, J. and Chiquet, M.: Structural motifs of the extracellular matrix proteins laminin and tenascin
In: Patterns in Protein Sequence and Structure (W.R. Taylor, ed.) Springer Series in Biophysics, Springer Verlag, vol. 7, pp. 229-254 (1992)
Hunter, I., Schulthess, T. and Engel, J.:
Laminin chain assembly by triple and double stranded coiled-coil structures
J. Biol. Chem. 267, 6006-6011 (1992)
Maurer, P., Mayer, U., Bruch, M., Jenö, P., Mann, K., Landwehr, R., Engel, J. and Timpl, R.:
High and low affinity calcium binding and stability of the multidomain extracellular glycoprotein BM40/SPARC/Osteonectin Eur. J. Biochem. 205, 233-240 (1992)
Mörgelin, M., Heinegard, D., Engel, J. and Paulsson, M.:
Electron microscopy of native COMP (cartilage oligomeric matrix protein) purified from the swarm rat chondrosarcoma reveals a five-armed structure J. Biol. Chem. 267, 6137-6141 (1992)
Engel, J.: Structure and function of laminin.
In: Molecular and Cellular Aspects of Basement Membranes. Chapter 8 (R. Timpl, D.H. Rohrbach, eds.), pp. 147-176 Academic Press (1993)
Engel, J.:
Extracellular matrix proteins and cell growth
Falk Symposium Series (A.M. Gressner, G. Ramdori, eds.) Kluwer Academic Publishers, pp. 495-503 (1992)
Mörgelin, M., Engel, J., Heinegard, D. and Paulsson, M.:
Proteoglycans from the Swarm rat chondrosarcoma: Structure of the aggregates extracted with associative and dissociative solvents as revealed by electron microscopy
J. Biol. Chem. 267, 14275-14284 (1992)
Engel, J.: Laminins and other strange proteins
Biochemistry 31, 10643-10651 (1992)
Engel, J.: Alpha helical coiled-coil domains connect protein subunits
Ciencia e Cultura 44, 239-241 (1992)
Specks, U., Mayer, U., Nischt, R., Spissinger, T., Mann, K., Timpl, Engel, J. and Chu, M.-L.:
Structure of recombinant N-terminal globule of collagen type VI α3 chain and its binding to heparin and hyaluronan EMBO J. 11 4281-4290 (1992)
Romanic, A.M., Adachi, E., Hojima, Y. and Engel, J. and Prockop, D.J.:
Polymerization of pNcollagen I and copolymerization of pNcollagen I with collagen I. A kinetic, thermodynamic and morphologic study J. Biol. Chem. 267, 22265-22271 (1992)
Pikkarainen, T., Schulthess, T., Engel, J. and Tryggvason, K.:
Recombinant laminin β1 chains exhibit intact short-arm domains but do not form oligomeric molecules Eur. J. Biochem. 209, 571-582 (1992)
1993
Müller, B., Zerwes, H.-G., Tangemann, K., Peter, J. and Engel, J.:
Two-step binding mechanism of fibrinogen to aIIbß3 integrin reconstituted into planar lipid bilayers J. Biol. Chem. 268, 6800-6808 (1993)
Beck, K., Dixon, T.W., Engel, J. and Parry, D.A.D.:
Ionic interactions in the coiled-coil domain of laminin determine the specificity of chain assembly J. Mol. Biol. 231, 311-323 (1993)
1994
Engel, J.: Concepts of self-assembly in biological systems
In: Biology of Extracellular Matrix (P.D. Yurchenco, D.E. Birk,R.P. Mecham, eds.) Academic Press pp. 1-14 (1994)
Auerbach, G., Gaill, F., Jaenicke, R., Schulthess, T., Timpl, R. and Engel, J.:
Pressure dependence of collagen melting
Matrix Biol. 14, 589-592 (1994)
Romanic, A.M., Spotila, L., Adachi, E., Engel, J., Hojima, Y. and Prockop, D.J.:
Self-assembly of collagen I from a proband homozygous for a mutation that substituted serine for glycine at position 661 in the α2(I) chain J. Biol. Chem.269, 11614-11619 (1994)
Lindblom, A., Marsh, T., Fauser, C., Engel, J. and Paulsson, M.:
Characterization of native laminin from bovine kidney and comparison with other laminin variants Eur. J. Biochem. 219, 383-392 (1994)
Pottgiesser, J., Maurer, P., Mayer, U., Nischt, R., Mann, K., Timpl, R., Krieg, T. and Engel, J.:
Changes in calcium and collagen IV binding caused by mutations in the EF hand and other domains of extracellular matrix protein BM-40 (SPARC, Osteonectin) J. Mol. Biol. 238, 563-574 (1994)
Hojima, Y., Mörgelin, M., Engel, J., Boutillon, M.-M., van der Rest, M., McKenzie, J.A., Chen, G.-Ch., Rafi, N., Romanic, A.M. and Prockop, D.J.:
Characterization of type I procollagen N-proteinase from the fetal bovine tendon and skin. Purification of 500-kDa form of the enzyme from bovine tendon and skin
J. Biol. Chem. 269, 11381-11390 (1994)
Mörgelin, M., Heinegard, D., Engel, J. and Paulsson, M.:
The cartilage proteoglycan aggregate: Assembly through combined protein-carbohydrate and protein-protein interactions Biophys. Chem. 50, 113-128 (1994)
Burgeson, R.E., Chiquet, M., Deutzmann, R., Ekblom, P., Engel, J., Kleinman, H., Martin, G.R., Meneguzzi, G., Paulsson, M., Sanes, J., Timpl, R. Tryggvason, K., Yamada, Y. and Yurchenco, P.D.: A new nomenclature for the laminins. Matrix Biol 14, 209-211 (1994)
Efimov, V.P., Lustig, A., and Engel, J.:
The thrombospondin-like chains of cartilage oligomeric matrix protein are assembled by a five-stranded α-helical bundle between residues 20 and 83. FEBS Lett. 341, 54-58 (1994)
Engel, J. Electron microscopy of extracellular matrix components.
Methods Enzymol. 245, 469-488 (1994)
Pfaff, M., Tangemann, K., Müller, B., Gurrath, M., Müller, G., Kessler, H., Timpl, R. and Engel, J.:
Selective recognition of cyclic RGD peptides of NMR defined conformation by aIIbß3,αVß3 andα5ß1 integrins J. Biol. Chem. 269, 20233-20238 (1994)
Efimov, V.P.,Nepluev, I.V., Sobolev, B.N., Zurabishvili, T.G., Schulthess, T., Lustig, A., Engel, J., Haener, M., Aebi, U.
Fibritin encoded by bacteriophage T4 gene wac has a parallel triple-stranded α-helical coiled-coil structure J. Mol. Biol. 242, 470-486 (1994)
Engel, J., Efimov, V. and Maurer, P.:
Domain organization of extracellular matrix proteins and their evolution. Development 120, Suppl. 35-42, (1994)
Pokutta, S., Herrenknecht, K., Kemler, R. and Engel, J.:
Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding Eur. J. Biochem.223, 1019-1026 (1994)
Kammerer, R.A., Antonsson, P., Schulthess, T. and Engel, J.
Sequential stabilization of the α-helical coiled-coil involved in chain assembly of laminin as revealed by recombinant fragments Matrix Biol. 14, 417-418 (1994)
Spissinger, T. and Engel, J.: Type IV collagen beaded microfibrils from bovine cornea depolymerize at acidic pH and depolymerization and polymerization are not influenced by hyaluronen Matrix Biol. 14, 499-505 (1994)
1995
Kammerer, R.A., Antonsson, P., Schulthess, T., Fauser, C. and Engel, J.:
Selective chain recognition in the C-terminal α-helical coiled-coil region of laminin.
J. Mol. Biol. 250, 64-73 (1995)
Gaill, F., Mann, K., Wiedemann, H., Engel, J. and Timpl, R.
Structural comparison of cuticle and interstitial collagens from annelids living in shallow sea water and at deep sea hydrothermal vents J. Mol. Biol. 246, 284-294 (1995)
Mörgelin, M., Paulsson, M., Heinegard, D., Aebi, U. and Engel, J.:
Evidence of a defined spatial arrangement of hyaluronate in the central filament of cartilage proteoglycan aggregates Biochem. J. 397, 595-601 (1995)
Antonsson, P., Kammerer, R.A., Schulthess, T., Hänisch, G. and Engel, J.:
Stabilization of the α-helical coiled-coil domain in laminin by C-terminal disulfide bonds
J. Mol. Biol., 250, 74-79 (1995)
Tangemann, K. and Engel, J.:
Demonstration of nonlinear detection in ELISA resulting in up to 1000-fold to high affinities of fibrinogen binding to integrin aIIbβ3 FEBS Lett. 358, 179-181 (1995)
Maurer, P., Hohenadl, C., Hohenester, E., Göhring, W., Timpl, R. and Engel, J.:
The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain which binds calcium and collagen IV
J. Mol. Biol. 253, 347-357 (1995)
Ries, A., Engel, J., Lustig, A. and Kühn, K.:
The function of the NC1 domains in type IV collagen
J. Biol. Chem. 270, 23790-23794 (1995)
Brancaccio, A., Schulthess, T., Gesemann, M. and Engel, J.:
Electron microscopic evidence for a mucin-like region in chick muscle a-dystroglycan
FEBS Lett. 368, 139-142 (1995)
Brancaccio, A., Rüegg, M.A. and Engel, J.:
Cloning and sequencing of mouse skeletal muscle α-dystroglycan
Matrix Biology 14, 681-685 (1995)
1996
Rivas, G., Tangemann, K., Minton, A.P. and Engel, J.:
Binding of fibrinogen to platelet integrin αIIbβ in solution as monitored by tracer sedimentation equilibrium.
J. Molec. Recogn. 9, 31-38 (1996)
Maurer, P. and Engel, J.:
Structure of laminins and their chain assembly
In: The laminins(eds. P. Ekblom and R. Timpl) Harwood Academic Publishers, 27-49 (1996)
Efimov, V.P., Engel, J. and Malashkevich, V.N.:
Crystallization and preliminary crystallographic study of the pentamerizing domain from cartilage oligomeric protein: a five-stranded α-helical bundle,
Proteins 24, 259-262 (1996)
Hohenester, E., Maurer, P., Hohenadl, C., Timpl, R., Jansonius, J.N. and
Engel J.:
Structure of a novel extracellular Ca2+-binding module in BM-40/SPARC/osteonectrin
Nature Struct. Biol. 3, 67-73 (1996)
Tangemann, K. and Engel, J.:
Binding studies of integrins with their respective ligands in Integrin-Ligand Interaction (Eble, J. and Kühn, K., eds.) Landes Bioscience Publishers, Georgetown Texas 1997, 85-100 (1997)
Tomschy, A., Fauser, C., Landwehr, R. and Engel, J.:
Homophilic adhesion of E-cadherin occurs by a cooperative two step interaction of N-termina domains
EMBO J. 15, 3507-3514 (1996)
Brandenberger, R., Kammerer, R., Engel, J. and Chiquet, M.:
Native chick laminin-4 containing the ß2 chain (s-laminin) promotes rather than inhibits motor axon growth
J. Cell Biol. 135, 1583-1592 (1996)
Malashkevich, V.N., Kammerer, R.A., Efimov, V., Schulthess T. and Engel, J.:
The crystal structure of a five-stranded coiled-coil in COMP: a prototype ion channel?
Science 274, 761-765 (1996)
Maurer, P., Hohenester E. and Engel, J.:
Extracellular calcium binding proteins
Current Opinion in Cell Biology 8, 609-617 (1996)
Jürgen Engel:
Domain organizations of modular extracellular matrix proteins and their evolution
Matrix Biol. 15, 295-299 (1996)
1997
Wiltscheck, R., Kammerer, R., Dames, S.A., Schulthess, T., Blommers, M.J.J., Engel, J. and Alexandrescu, A.T.:
Heternonuclear NMR assignments and secondary structure of the coiled coil trimerization domain from cartilage matrix protein in oxidized and reduced forms
Protein Sci. 6, 1734-1745 (1997)
Erb, E.-M., Tangemann, K., Bohrmann, B., Müller, B. and Engel, J.:
The integrin αIIbβ3 reconstituted into lipid bilayers is non-clustered in its activated state but clusters after fibrinogen binding
Biochemistry 36, 7395-7402 (1997)
Sasaki, T., Mann, K., Wiedemann, H., Göring, W., Lustig, A., Engel, J.,
Chu, M.-L. and Timpl, R.:
Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge
EMBO J. 16, 3035-3043 (1997).
Brancaccio, A., Schulthess, T., Gesemann, M. and Engel, J.:
The N-terminal region of α-dystroglycan is an autonomous globular domain
Eur. J. Biochem. 246, 166-172 (1997)
Koch, A.W., Pokutta, S., Lustig, A. and Engel J.:
Calcium binding and homoassociation of E-cadherin domains
Biochemistry 36, 7697-7705 (1997)
Engel J.:
Versatile Collagens in Invertebrates
Science 277, 1785-1786 (1997)
1998
Sasaki, T., Brakebusch, C., Engel J. and Timpl, R.:
Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds β1 integrins, collagens and fibronectin
EMBO J. 17, 1606-1613 (1998)
Engel J.:
Networks of extracellular matrix and adhesion proteins Dynamical Networks in Physics and Biology (eds. B. Beysens, G. Forgacs)
Springer, Berlin, 131-137 (1998)
Koch, A.W., Holstein, T.W., Mala, C., Kurz, E., Engel, J. and David, C.N.
Spinalin, a new glycine and histidine rich protein in spines of Hydra nematocysts
J. Cell Sci. 111, 1545-1554 (1998)
Denzer, A.J., Schulthess, T., Fauser, C., Schumacher, B., Kammerer, R.A., Engel J. and Ruegg, M.A.
Electron microscopic structure of agrin and mapping of its binding site in laminin-1
EMBO J. 17, 335-343 (1998)
Brancaccio, A., Jenö, P. and Engel J.:
A single disulfide bridge (Cys182-Cys264) is crucial for α-dystroglycan N-terminal domain stability
Ann. N.Y. Acad. Sci., 857, 228-231 (1998)
Guo, Y., Bozic, D., Malashkevich, V., Kammerer, R.A., Schulthess, T., and Engel J.:
All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein
The EMBO J. 17, 5265-5272 (1998)
Kammerer, R.A., Schulthess, T., Landwehr, R., Lustig, A., Fischer, D. and
Engel J.:
Tenascin-C hexabrachion assembly is a sequential two-step process initiated by coiled-coil α-helices
J. Biol. Chem. 273, 10602-10608 (1998)
Dames, S., Kammerer, R.A., Wiltscheck, R., Engel J., and Alexandrescu, A.T.:
NMR structure of a parallel homotrimeric coiled-coil
Nat. Struct. Biol. 5, 687-691 (1998)
Bozic, D., Engel, J. and Brancaccio, A.:
Sequence analysis suggests the presence of an IG-like module in the N-terminal region of α-dystroglycan which was crystallized after mutation of a protease susceptible site (Arg168 => His) Matrix Biol., 17, 495-500 (1998)
Engel J. and Prockop, D.:
Does bound water contribute to the stability of collagen and many other proteins?
Matrix Biol., 17, 679-680 (1998)
Kammerer, R.A., Schulthess, T., Landwehr, R., Lustig, A., Engel, J., Aebi, U., and Steinmetz, M.O.:
An autonomous folding unit mediates the assembly of two-stranded coiled-coils.
Proc. Natl. Acad. Sci. 95, 1349-13424 (1998)
1999
Koch A., Bozic, D., Pertz, O. and Engel, J.:
Homophilic adhesion by cadherins
Curr. Op. Struct. Biol., 9, 275-281 (1999)
Engel, J. and Bozic, D.:
Modules in extracellular matrix and adhesion molecules
In: Guidebook to the Extracellular Matrix and Adhesion Proteins (Kreis, T. and Vale, R., eds), Oxford University Press, 344-351 (1999).
Pihlajamaa, T., Perälä, M., Vuoristo, M., Nokelainen, M., Bodo, M., Schulthess, T., Vuorio, E., Engel, J. and Ala-Kokko, L.:
Characterization of recombinant human type IX collagen. Association of α-Chains into homotrimeric and heterotrimeric molecules
J. Biol. Chem., 274, 22464-22468 (1999)
Pertz, O., Bozic, D., Koch, A.W., Fauser, C., Brancaccio, A. and Engel, J.:
A new crystal structure Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation
EMBO J., 18, 1738-1747 (1999)
Engel, J. and Bächinger, H.P.:
Collagen-like sequences in phages and bacteria
Proc. Indian Acad Sci. 111, 81-86 (1999)
Dames, S.A., Kammerer, R.A., Moskau, D., Engel, J., Alexandrescu, A.T.:
Contributions of the ionization states of acidic residues to the stability of the coiled coil domain matrilin-1 FEBS Lett. 446, 75-80 (1999)
Kammerer, R.A., Frank, S., Schulthess, T., Landwehr, R., Lustig, A. and Engel, J.:
Heterodimerization of a functional metabotropic B-type g-aminobutyric acid (GABAB) receptor is mediated by parallel coiled-coil α-helices. Biochemistry 38, 13263-13269 (1999)
Müller, S.A., Sasaki, T., Bork, P., Wolpensinger, B., Schulthess, T., Timpl, R., Engel, A. and Engel, J.: Domain organization of Mac-2 binding protein and its oligomerization to linear and ring-like structures J. Mol. Biol. 291, 801-813 (1999)
Kammerer, R.A., Schulthess, T., Landwehr, R., Schumacher, B., Lustig, A., Yurchenco, P.D., Ruegg, M.A., Engel, J., and Denzer, A.J.:
Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin g1 chain EMBO J., 18, 6762-6770 (1999)
2000
Engel, J. and Bächinger, H.P.:
Cooperative equilibrium transitions coupled with a slow annealing step explain the sharpness and hysteresis of collagen folding Matrix Biology, 19, 235-244 (2000)
Holler, N., Kataoka, T., Bodmer, J.-L., Romero, P., Romero, J., Deperthes, D., Engel, J., Tschopp, J., and Schneider:
Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors J. Immunol. Meth., 237, 159-173 (2000)
Frank, S., Kammerer, R.A., Hellstern, S., Pegoraro, S., Stetefeld, J., Lustig, A., Moroder, L., and Engel, J.: Toward a High-Resolution Structure of Phospholamban: Design of Soluble Transmembrane Domain Mutants. Biochemistry 39, 6825-31(2000)
Frank, S., Lustig, A., Schulthess, T., Engel, J., and Kammerer, R.A.:
A distinct seven-residue trigger sequence is indispensable for proper coiled-coil formation of the human macrophage scavenger receptor oligomerization domain.
J. Biol. Chem., 275, 11672-11677 (2000)
Hall, H., Bozic, D., Fauser, C., and Engel, J.:
Trimerization of cell adhesion molecule L1 mimics clustered L1 expression on the cell surface: influence on L1-ligand interactions and on promotion of neurit outgrowth
J. of Neurochem., 75, 336-346 (2000)
Erb, E., Engel J.:
Reconstitution of Functional Integrin into Phospholipid Vesicles and Planar Lipid Bilayers
Methodes in Molecular Biology, 139, 71-82 Extracellular Matrix Protocols, Humana Press; Totowa, New Jersey (2000)
Frank S., Kammerer R. A., Hellstern S., Pegoraro St., Stetefeld J., Lustig A., Moroder L., Engel J.
Toward a High-Resolution Structure of Phospholamban: Design of Soluble Transmembrane Domain Mutants
Biochemistry, 39, 6825-6831 (2000)
Engel J., Kammerer R.
What are oligomerization domains good for?
Matrix Biology, 19, 283-288 (2000)
Stetefeld J., Jenny M., Schulthess Th., Landwehr R., Engel J., Kammerer R.
Crystal structure of a naturally occuring parallel right-handed coiled coil tetramer
Nature Structural Biology. 7, 772-776 (2000)
Guo Y., Kammerer R. A., Jürgen Engel J.
The unusually stable coiled-coil domain of COMP exhibits cold and heat denaturation in
4-6 M guanidinium chloride
Biophysical Chemistry 85, 179-186 (2000) 179-186
Koch A. W., Engel J., Maurer P.
Calcium Binding to Extracellular Matrix
Proteins, Functional and Pathological Effects
The Molecular Basis of Calcium Action in Biology and Medicine 151-164
Kluwer Academic Publishers (2000)
2001
Engel U., Pertz O., Fauser C., Engel J., David C.N., Holstein T.W.,
A switch in disulfide linkage during minicollagen assembly in Hydra nematocysts
EMBO J, 20, 3063-3073 (2001)
W.A. Wells J. Cell Biol. 154, 13, (2001) review of Engel, U., Pertz, O., Fauser, C., Engel, J., David, C. N. and Holstein, T. W.: A switch in disulfide linkage during minicollagen assembly in Hydra nematocysts EMBO J. 20, 3063-3073 (2001)
Frank S., Kammerer R. A., Mechling D., Schulthess Th., Landwehr R., Bann J., Guo Y., Lustig A., Bächinger H. P., Engel J. Stabilization of short collagen-like helices by protein engineering, J. Mol. Biol. 308, 1081-1089 (2001)
Hellstern S., Pegoraro St., Karim Chr. B., Lustig A., Thomas, D.D., Moroder L., Engel J.
Sarcolipin, the Shorter Homologue of Phospholamban, Forms Oligomeric Structures in detergent Micelles and in Liposomes J Biol Chem. 2001 276, 30845-52 (2001)
Stetefeld J., Jenny M., Schulthess Th., Landwehr R., Schumacher B., Frank S., Rüegg Markus A., Engel J. and Kammerer R.A. The Laminin Binding Domain of Agrin Is Structurally Related to N-TIMP-1 Nat Struct Biol. 8 705-9 (2001)
Kammerer R. A., Jaravine A. V., Frank S., Schulthess Th., Landwehr R., Lustig A., Garchia-Echeverria C., Alexandrescu. A. T., Engel J., Steinmetz M. O.
An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper
J. of Biol. Chem., 17 , 276,13685-8 (2001)
Alexandrescu Andrei T., Maciejewski Mark W., Rüegg Markus A., Engel J., Kammerer Richard A.
1H, 13C and 15N backbone assignments for the C-terminal globular domain of agrin
Journal of Biomolecular NMR, 20, 295-296 (2001)
Bächinger H. P.and Engel J. Thermodynamic vs. kinetic stability of collagen triple helices
Matrix Biology, 20, 267-269 (2001)
2002
Boudko P. B., Londer Y. Y., Letarov A. V., Senova N. V., Lustig A., Engel J., Mesyanzhinov V. V Stabiltiy and Domain Organization of Bacteriophage T4 Fibritin, a Segmented Coiled-Coil Protein Eur J Biochem., 26, 9833-41 (2002)
Özbek, S., Engel, U. and Engel, J.: A switch in disulfide linkage during minicollagen assembly in Hydra nematocysts or how to assemble a 150 bar resistent structure
J. Struct. Biol. 137, 11-14 (2002)
Ahrens, T., Pertz, O., Häussinger, D., Fauser, C., Schulthess, T. and Engel, J.:
Analysis of heterophilic and homophilic interactions of cadherins using the c-Jun/c-Fos dimerization domains J. Biol. Chem. 277, 19455-19460 (2002)
Hellstern, S., Sasaki, T., Fauser, C., Lustig, A., Timpl, R. and Engel, J.:
Functional studies on recombinant domains of Mac-2 binding protein
J. Biol. Chem. 277, 15690-15696 (2002)
Frank, S., Schulthess, T., Landwehr, R., Lustig, A., Mini, T., Jenö, P., Engel, J. and Kammerer, R. A.: Characterization of the matrilin coiled-coil domains reveals seven novel isoforms J. Biol. Chem. 277, 19071-19079 (2002)
Hohenester, E. and Engel, J.:
Domain structure and organisation in extracellular matrix proteins
Matrix Biol. 21, 115-128 (2002)
Whittard, J. D., Craig, S. D., Mould, A. P., Koch, A., Pertz, O., Engel, J. and Humphries, M. J.: E-cadherin is a ligand for integrin α2β1 Matrix Biology, 21, 525-532 (2002)
Sankala, M., Brännström, A., Schulthess, T., Bergmann, U., Morgunova, E., Engel, J., Tryggvason, K. and Pikkarainen, T.: Characterization of recombinant soluble macrophage scavenger receptor MARCO J. Biol. Chem. 277, 33378-33385 (2002)
Feng, K., Zhou, X.-H., Oohashi, T., Mörgelin, M., Lustig, A., Hirakawa, S., Ninomiya, Y., Engel, J., Rauch, U. and Fässler, R.: All four members of the Ten-m/Odz family of transmembrane proteins form dimers J. Biol. Chem. 277, 26128-26135 (2002)
Boudko, S., Frank, S., Kammerer, R. A., Stetefeld, J., Schulthess, T., Landwehr, R., Lustig, A., Bächinger, H. P. and Engel, J.: Nucleation and propagation of the collagen triple helix in single-chain and trimerized peptides: transition from third to first order kinetics J. Mol. Biol. 317, 459-470 (2002)
Häussinger, D., Ahrens, T., Sass, H.-J., Pertz, O., Engel, J. and Grzesiek, S.: Calcium-dependent homoassociation of E-cadherin by NMR spectroscopy: changes in mobility, confirmation and mapping of contact regions J. Mol. Biol. 324, 823-839 (2002)
Engel, U., Özbek, S., Engel, R., Petri, B., Lottspeich, F. and Holstein, T. W.: Nowa, a novel protein with minicollagen Cys-rich domains is involved in nematocysts formation in Hydra J.
Cell Sci. 115, 3923-3934 (2002)
Özbek, S., Engel, J. and Stetefeld, J.: Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D3 EMBO J. 21, 5960-5968 (2002)
Özbek, S., Pertz, O., Schwager, M., Lustig, A., Holstein, T. and Engel, J: Structure relationships in the minicollagen of hydra nematocysts.
J. Biol. Chem. 277, 49200-49204 (2002)
2003
Adams, J. C., Monk, R., Taylor, A. L., Özbek, S., Fascetti, N., Baumgartner, S. and Engel, J.: Characterisation of Drosophila thrombospondin defines an early origin of pentameric thrombospondins
J. Mol. Biol. 328, 479-494 (2003)
Holler, N., Tardivel, A., Kovacovics, M., Hertig, S., Gaide, O., Calderara, S., Schulthess, T., Engel, J., Schneider, P. and Tschopp, J.:
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of the death-inducing signaling complex
Mol. Cell Biol. 23, 1428-1440 (2003)
Ahrens, T., Lambert, M., Pertz, O., Sasaki, T., Schulthess, T., Mège, R.-M., Timpl, R. and Engel, J.: Homoassociation of VE-cadherin Follows a Mechanism Common to “Classical” Cadherins
J. Mol. Biol. 325, 733-742 (2003)
Frank, S., Boudko, S., Mizuno, K., Schulthess, T., Engel, J. and Bächinger, H. P.
Collagen Triple Helix Formation Can Be Nucleated at Either End
J. Biol. Chem. 278, 7747-7750 (2003)
Pajvani, U. B., Du, X., Combs, T. P., Berg, A. H., Rajala, M. W., Schulthess, T., Engel, J., Brownlee, M. and Scherer, P. E.: Structure-Function Studies of the Adipocyte-secreted Hormone Acrp30/Adiponectin: Implications for metabolic regulation and bioactivity
J. Biol. Chem. 278, 9073-9085 (2003)
Häussinger, D., Ahrens, T., Aberle, T., Engel, J., Stetefeld, J. and Grzesiek, S. Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography
EMBO J. 23, 1699-1708(2004)
Mascarenhas, J. B., Rüegg, M. A., Winzen, U., Halfter, W., Engel, J. and Stetefeld J.: Mapping of the laminin-binding site of the N-terminal agrin domain (NtA)
EMBO J. 22, 1-8 (2003)
Stetefeld, J., Frank, S., Jenny, M., Schulthess, T., Kammerer, R. A., Boudko, S., Landwehr, R., Okuyama, K. and Engel, J.: Collagen Stabilization at Atomic Level. Crystal Structure of Designed (GlyProPro) (10)foldon Structure (Camb) 11, 339-346 (2003)
2004
Özbek, S., Pokidysheva, E., Schwager, M., Schulthess, T., Anjum, N., Engel, J. and Holstein, T.: Structure and assembly of the Hydra nematocyst wall J Biol Chem. 279, 52016-23 (2004)
Boudko, S. and Engel, J.: Structure Formation in the C-Terminus of Type III Collagen Guides Disulfide Cross-Linking
J. Mol. Biol. 335, 1289-1297 (2004)
Engel, J.: Role of oligomerization domains in thrombospondins and other extracellular matrix proteins Int. J. Biochem.
Cell Biol. 36, 997-1004 (2004)
Mann, H. H., Özbek, S., Engel, J., Paulsson, M. and Wagener, R. Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias J. Biol. Chem. 279, 25294-25298 (2004)
Boudko, S., Strelkov, S., Engel, J. and Stetefeld, J.: Design and crystal structure of bacteriophage T4 mini-fibritin NCCF
J. Mol. Biol. 339, 927-935 (2004)
Ahrens, T., Stetefeld, J., Häussinger, D. and Engel, J.:
The superfamily of Cadherins: calcium-dependent cell adhesion receptors Handbook of metalloproteins 3, 731-741,
John Wiley & Sons, Ltd. (2004)
Pokidysheva, E., Milbradt, A. G., Meier, S., Renner, C., Haussinger, D., Bächinger, H. P., Moroder, L., Grzesiek, S., Holstein, T. W., Özbek, S. and Engel, J.:
The structure of the Cys-rich terminal domain of Hydra minicollagen, which is involved in disulfide networks of the nematocyst wall
J.Biol. Chem. 279, 30395-30401 (2004)
2005
Bächinger, H. P. and Engel, J.: Thermodynamics and kinetics of collagen folding in Handbook of Protein Folding (eds. Buchner,J. and Kiefhaber, T.)
Wiley-VCH Weinheim, Vol. 2, pp. 1059 - 1110 (2005).
Engel, J. and Bächinger, H. P.: Structure, Stability and Folding of the Collagen Triple Helix
Topics in Current Chemistry, Collagen (Brinckmann, J., Notbohm, H., Müller, P. K. eds.),
Springer 247, 7 - 34. (2005)
Aumailley M, Bruckner-Tuderman L, Carter WG, Deutzmann R, Edgar D, Ekblom P, Engel J, Engvall E, Hohenester E, Jones JC, Kleinman HK, Marinkovich MP, Martin GR, Mayer U, Meneguzzi G, Miner JH, Miyazaki K, Patarroyo M, Paulsson M, Quaranta V, Sanes JR, Sasaki T, Sekiguchi K, Sorokin LM, Talts JF, Tryggvason K, Uitto J, Virtanen I, von der Mark K, Wewer UM, Yamada Y, Yurchenco PD.: A simplified laminin nomenclature.
Matrix Biol. 24,326-32.(2005)
Mascarenhas J.B., Ruegg M. A., Sasaki T., Eble J.A., Engel J., Stetefeld J.: Structure and laminin-binding specificity of the NtA domain expressed in eukaryotic cells.
Matrix Biol. 23, 507-13 (2005)
Bachmann A., Kiefhaber T., Boudko S., Engel J., Bachinger H.P.: Collagen triple-helix formation in all-trans chains proceeds by a nucleation/growth mechanism with a purely entropic barrier
Proc Natl Acad Sci U S A. 102, 13897-902 (2005)
2007
Meier S, Jensen PR, Adamczyk P, Bächinger HP, Holstein TW, Engel J, Ozbek S, Grzesiek Sequence-structure and structure-function analysis in cysteine-rich domains forming the ultrastable nematocyst wall.
J Mol Biol. 2007 368 718-28 (2007)
Adam J., C. and Engel J.: Bioinformatic analysis of adhesion proteins. Methods Mol Biol. 370, 147-72 (2007)
Engel J.: Visions for novel biophysical elucidations of extracellular matrix networks.
Int J Biochem Cell Biol. 39, 311-8 (2007)
2008
Mizuno K., Peyton D.H., Hayashi T., Engel J., Bächinger H.P.: Effect of the -Gly-3(S)-hydroxyprolyl-4(R)-hydroxyprolyl- tripeptide unit on the stability of collagen model peptides.
FEBS J. 275, 5830-40 (2008)
Boudko S.P., Engel J., Bächinger H.P.: Trimerization and triple helix stabilization of the collagen XIX NC2 domain.
J Biol Chem. 283, 34345-51 (2008)
Boudko S.P., Engel J., Okuyama K., Mizuno K., Bächinger H.P., Schumacher M.A.: Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries.
J Biol Chem. 283, 32580-9 (2008)
2009
Okuyama K., Bächinger H.P., Mizuno K., Boudko S., Engel J., Berisio R., Vitagliano L.: Re: Microfibrillar structure of type I collagen in situ.
Acta Crystallogr D Biol Crystallogr. 65 1007-8 (2009)
Boudko S.P., Sasaki T., Engel J., Lerch T.F., Nix J., Chapman M.S., Bächinger H.P. Crystal structure of human collagen XVIII trimerization domain: A novel collagen trimerization Fold.
J Mol Biol. 392, 787-802 (2009)
2010
Mizuno K., Boudko S.P., Engel J., Bächinger H.P.: Kinetic hysteresis in collagen folding.
Biophys J. 98 3004-14 (2010)
Boudko S.P., Zientek K.D., Vance J., Hacker J.L., Engel J., Bächinger H.P.: The NC2 domain of collagen IX provides chain selection and heterotrimerization.
J Biol Chem. 285 23721-31 (2010)
2012
Boudko S. P., Engel J., Bächinger H. P.: The crucial role of trimerization domains in collagen folding. Int J Biochem Cell Biol. 44 21-32 (2012)
2013
Mizuno K, Boudko S, Engel J, Bächinger HP. Vascular Ehlers-Danlos syndrome mutations in type III collagen differently stall the triple helical folding.
J Biol Chem.288 19166-76 (2013)
